What are the properties of a nicotinic acetylcholine receptor?

admin August 30, 2022

The properties of a nicotinic acetylcholine receptor are as given below:

5 subunits, each subunit has 4 transmembrane domains

Cysteine rich loop

Ach binds to the alpha subunit

Alpha x2, beta, gamma and delta

Wide mouth, narrow selectivity

Permeable to Na+

Antagonist- bungarotoxin and Tubocararine

Agonist- nicotine (causes spontaneous contraction)

Bzzii