Which of the following amino acid substitution is responsible for causing sickle cell anemia? | Biology


Which of the following amino acid substitution is responsible for causing sickle cell anemia? 

A. Valine is substituted by Glutamic acid in the α globin chain at the sixth position 
B. Valine is substituted by Glutamic acid in the β globin chain at seventh position 
C. Glutamic acid is substituted by Valine in the α globin chain at the sixth position 
D. Glutamic acid is substituted by Valine in the β globin chain at the sixth position
 






D. Glutamic acid is substituted by Valine in the β globin chain at the sixth position
 
Explanation:
Glutamic acid is substituted by Valine in the β globin chain at the sixth position is the following amino acid substitution is responsible for causing sickle cell anemia.





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